Venom anaphylaxis

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467 Clinical Case. Bee Venom Anaphylaxis

CAP value among the 3 groups. MANOVA multivariate analysis evaluated differences in overall CAPs and the effects of age, gender, Mueller grade and stings number. A P , 0.05 was considered statistically significant. Data were analysed by ‘SPSS’ 13.0 (SPSS Inc., Chicago, IL). We called NS patients to check if they were stung after VIT discontinuation. Results: We selected 84 NS, 72 SP3 and 76 SP5...

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Wasp venom allergy: effect of anti-IgE antibody on wasp venom anaphylaxis in a mouse model.

BACKGROUND Although anti-IgE antibody (Ab) therapy was recently shown to be effective in patients with bronchial asthma, no study has reported the effect of IgE therapy in the prevention of wasp venom anaphylaxis. In this study, we used a mouse model of wasp venom allergy to investigate the effect of anti-IgE Ab on wasp venom anaphylaxis. METHODS We developed a mouse model of wasp venom aller...

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Anaphylaxis to Insect Venom Allergens: Role of Molecular Diagnostics

Anaphylaxis due to Hymenoptera stings is one of the most severe consequences of IgE-mediated hypersensitivity reactions. Although allergic reactions to Hymenoptera stings are often considered as a general model for the underlying principles of allergic disease, diagnostic tests are still hampered by a lack of specificity and venom immunotherapy by severe side effects and incomplete protection. ...

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IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity.

BACKGROUND Type 2 cytokine-related immune responses associated with development of antigen-specific IgE antibodies can contribute to pathology in patients with allergic diseases and to fatal anaphylaxis. However, recent findings in mice indicate that IgE also can enhance defense against honeybee venom. OBJECTIVE We tested whether IgE antibodies, IgE-dependent effector mechanisms, and a local ...

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Age-dependent sting recurrence and outcome in immunotherapy-treated children with anaphylaxis to Hymenoptera venom.

BACKGROUND Data on outcome of insect venom immunotherapy in children are rare. OBJECTIVE We investigated the rate of sting recurrence and outcome of Hymenoptera venom anaphylaxis in children of different age groups treated with immunotherapy. METHODS Data from children consecutively referred for anaphylaxis to Hymenoptera venom were collected using a standardized questionnaire. RESULTS Du...

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ژورنال

عنوان ژورنال: Canadian Medical Association Journal

سال: 2015

ISSN: 0820-3946,1488-2329

DOI: 10.1503/cmaj.141264